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CyFlow™ CD2 APC-Cy7

CyFlow™ CD2 APC-Cy7
Application: Flow cytometry
Clonality: monoclonal
Target Species: Human
Regulatory Status: RUO
Source Species: Mouse
Field of Interest: Immunophenotyping
Laser: Red
Isotype: IgG1
Antigen: CD2
Alternative Name: LFA-2
Clone: TS1/8
Format/Fluorochrome: APC-Cy7
Excitation Maximum: 650 nm, 750 nm
Emission Maximum: 780 nm
Order number: CR042022
HLDA Workshop HLDA V—WS Code S025 Quantity 100 tests Volume 0.4 mL Immunogen... more
Product information "CyFlow™ CD2 APC-Cy7"
HLDA WorkshopHLDA V—WS Code S025
Quantity100 tests
Volume0.4 mL
ImmunogenCytotoxic T lymphocytes
Background InformationCD2 (LFA-2) belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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* All prices are quoted net of the statutory value-added tax and shipping costs and possibly delivery charges, if not otherwise described

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